SCHEMBL29601544

SCHEMBL29601544

NCc1cc(-c2ccccc2F)n(S(=O)(=O)c2cccnc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
GAA P10253 2/20 0.38
KMT2A Q03164 1/20 0.38
HTR6 P50406 1/20 0.36
KDR P35968 1/20 0.35
EPHB4 P54760 1/20 0.35
TEK Q02763 1/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
GPBAR1 Q8TDU6 2/20 0.34
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28054466 1.00 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4GAA
Dimethylamine SCHEMBL28372138 0.96 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4GAA
Fumaric Acid SCHEMBL21931373 0.92 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4GAA
Fumaric Acid SCHEMBL30833006 0.92 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA3CHRNA4GAA
SCHEMBL29140304 0.89 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4GAA
SCHEMBL30789010 0.89 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4GAA
SCHEMBL30620798 0.89 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4GAA
SCHEMBL29601011 0.89 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4GAA
SCHEMBL28857086 0.89 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA3CHRNA4GAA
SCHEMBL28269615 0.89 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853728-B Vonopraz fumarate tablet and preparation method thereof 四川制药制剂有限公司 2023-11-07 CN claimed
CN-115448907-A Compound for treating peptic ulcer, intermediate and preparation method 赛隆药业集团股份有限公司 2022-12-09 CN claimed
CN-110200903-B Liquid formulations of amines and organic acids stabilized with salts 武田药品工业株式会社 2022-07-29 CN claimed
CN-121574094-B Rebamipide Fu Nuola raw salt and preparation method and application thereof 湖南先施制药有限公司 2026-05-19 CN disclosed
CN-121574094-A Rebamipide Fu Nuola raw salt and preparation method and application thereof 湖南先施制药有限公司 2026-02-27 CN disclosed
WO-2025134080-A1 PREPARATION OF HIGHLY PURE VONOPRAZAN FUMARATE SUBSTANTIALLY FREE OF IMPURITIES SYMED LABS LIMITED (IN) 2025-06-26 WO disclosed
CN-115448907-B Compound for treating peptic ulcer, intermediate and preparation method thereof 赛隆药业集团股份有限公司 2024-01-12 CN disclosed
CN-114853728-B Vonopraz fumarate tablet and preparation method thereof 四川制药制剂有限公司 2023-11-07 CN disclosed
CN-115448907-A Compound for treating peptic ulcer, intermediate and preparation method 赛隆药业集团股份有限公司 2022-12-09 CN disclosed
CN-115448907-A Compound for treating peptic ulcer, intermediate and preparation method 赛隆药业集团股份有限公司 2022-12-09 CN disclosed
CN-110200903-B Liquid formulations of amines and organic acids stabilized with salts 武田药品工业株式会社 2022-07-29 CN disclosed
CN-114149412-A Intermediate compound for preparing Vonoprazan 鲁南制药集团股份有限公司 2022-03-08 CN disclosed