SCHEMBL28857152

SCHEMBL28857152

C=CC(=O)ONC(N)=O.C=CCC

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.38
HPGD P15428 1/20 0.38
MAPT P10636 2/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
ALDH1A1 P00352 6/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
FGFR4 P22455 1/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 3/20 0.33
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32691366 0.87 TSHR (0.43) TSHRHPGDMAPTCACNA1BAPBA1
SCHEMBL190486 0.87
SCHEMBL32691321 0.87 TSHR (0.43) TSHRHPGDMAPTCACNA1BAPBA1
SCHEMBL28857108 0.77 ALDH1A1 (0.40) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL28220847 0.75 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28124809 0.73 MAPT (0.45) TSHRMAPTCACNA1BAPBA1ALDH1A1
Acrylamide SCHEMBL27513270 0.73 TSHR (0.65) TSHRHPGDMAPTCACNA1BAPBA1
Acrylamide SCHEMBL2860199 0.73
Urea SCHEMBL4967947 0.72
SCHEMBL28838342 0.72 CTSD (0.45) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114149532-A Acrylic resin containing epoxy group and ethylene ureido group, preparation method and application thereof 中国海洋大学 2022-03-08 CN claimed
CN-114149532-A Acrylic resin containing epoxy group and ethylene ureido group, preparation method and application thereof 中国海洋大学 2022-03-08 CN disclosed
CN-114149532-A Acrylic resin containing epoxy group and ethylene ureido group, preparation method and application thereof 中国海洋大学 2022-03-08 CN disclosed