Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.46 |
| ▸ | WNT3A | P56704 | 8/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | USP9X | Q93008 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28267549 | 0.98 | CTNNB1 (0.44) | CTNNB1WNT3AKEAP1NFE2L2ITGB2 | |
| SCHEMBL1784992 | 0.91 | CTNNB1 (0.44) | CTNNB1WNT3AKEAP1NFE2L2ITGB2 | |
| Sulfuric Acid SCHEMBL27858419 | 0.89 | CTNNB1 (0.47) | CTNNB1WNT3AKEAP1NFE2L2ITGB2 | |
| SCHEMBL27350794 | 0.89 | ITGB2 (0.50) | CTNNB1WNT3AITGB2ICAM1ITGAL | |
| Trifluoromethanesulfonic Acid SCHEMBL6467822 | 0.87 | CTNNB1 (0.43) | CTNNB1WNT3AKEAP1NFE2L2ITGB2 | |
| SCHEMBL27655123 | 0.87 | ITGB2 (0.48) | CTNNB1WNT3AITGB2ICAM1ITGAL | |
| SCHEMBL8447 | 0.87 | ITGB2 (0.52) | CTNNB1WNT3AITGB2ICAM1ITGAL | |
| SCHEMBL5313090 | 0.87 | ITGB2 (0.52) | CTNNB1WNT3AITGB2ICAM1ITGAL | |
| SCHEMBL29356442 | 0.87 | ITGB2 (0.52) | CTNNB1WNT3AITGB2ICAM1ITGAL | |
| SCHEMBL28007596 | 0.87 | ITGB2 (0.52) | CTNNB1WNT3AITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107683192-A | Antimycotic synergist | 拱木保护有限公司 | 2018-02-09 | — | — | CN | disclosed |