Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 12/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28207047 | 0.84 | HTR6 (0.63) | RORCHTR6MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL28207043 | 0.84 | RORC (0.56) | RORCHTR6MEN1KMT2AHTT | |
| SCHEMBL30159156 | 0.81 | HTR6 (0.68) | HTR6MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL706426 | 0.81 | HTR6 (0.68) | HTR6MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL45741 | 0.80 | HTR6 (0.63) | RORCHTR6MEN1KMT2AHTT | |
| SCHEMBL31319736 | 0.80 | HTR6 (0.63) | RORCHTR6MEN1KMT2AHTT | |
| SCHEMBL3621863 | 0.79 | HTR6 (0.50) | RORCHTR6HTTCA1CA2 | |
| SCHEMBL1444197 | 0.77 | HTR6 (0.61) | RORCHTR6MEN1KMT2AHTT | |
| SCHEMBL16619154 | 0.76 | KDM4E (0.44) | RORCHTR6HTTL3MBTL1PKM | |
| SCHEMBL9270506 | 0.74 | HTT (0.70) | HTR6MEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | disclosed |