SCHEMBL2885758

SCHEMBL2885758

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(-c4ccc(-c5ccc(N(c6ccc(C)cc6)c6ccc(C)cc6)cc5)s4)s3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APP P05067 10/20 0.51
HSD17B1 P14061 6/20 0.51
HSD17B2 P37059 6/20 0.51
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
MAPT P10636 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
ESRRG P62508 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7264517 1.00 APP (0.51) APPHSD17B1HSD17B2ESR1ESR2
SCHEMBL1573837 1.00 APP (0.51) APPHSD17B1HSD17B2ESR1ESR2
SCHEMBL2905343 0.98 HSD17B1 (0.53) APPHSD17B1HSD17B2ESR1ESR2
SCHEMBL13125840 0.89 APP (0.54) APPHSD17B1HSD17B2MAPT
SCHEMBL12125122 0.88 HSD17B1 (0.49) APPHSD17B1HSD17B2MAPTALDH1A1
SCHEMBL13937486 0.87 HSD17B1 (0.45) APPHSD17B1HSD17B2ESR1ESR2
SCHEMBL10109359 0.87 APP (0.56) APPHSD17B1HSD17B2MAPTALDH1A1
SCHEMBL17051482 0.87 APP (0.56) APPHSD17B1HSD17B2MAPTALDH1A1
SCHEMBL12575567 0.87 APP (0.52) APPHSD17B1HSD17B2ESR1ESR2
SCHEMBL14565390 0.87 APP (0.46) APPHSD17B1HSD17B2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6578406-B2 Multilayer stacks; colorimetric analysis of vapors REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-06-17 US claimed
US-6160267-A Vapochromic led REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2000-12-12 US claimed
US-20140318621-A1 SOLAR CELL MODULE AND PHOTOVOLTAIC POWER GENERATION DEVICE SHARP KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed
US-20140318601-A1 LIGHT GUIDE BODY, SOLAR CELL MODULE, AND SOLAR PHOTOVOLTAIC POWER GENERATION DEVICE SHARP KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed
US-20100283386-A1 DISPLAY DEVICE AND COMPOSITION FOR PRODUCING DISPLAY DEVICE, AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-11-11 US disclosed
US-6578406-B2 Multilayer stacks; colorimetric analysis of vapors REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-06-17 US disclosed
US-20020042174-A1 Vapochromic LED NATIONAL SCIENCE FOUNDATION 2002-04-11 US disclosed
US-6160267-A Vapochromic led REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2000-12-12 US disclosed