Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857632 | 0.88 | IMPDH2 (0.46) | TNIKLMNAHTTPOLB | |
| SCHEMBL28857603 | 0.87 | MEN1 (0.45) | TNIKRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28857574 | 0.86 | MGLL (0.48) | RAB9ANPC1SMN1; SMN2MAPTLMNA | |
| SCHEMBL28857617 | 0.85 | ESR1 (0.43) | RAB9ANPC1MAPTLMNAHTT | |
| SCHEMBL29898258 | 0.84 | POLB (0.49) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL28857616 | 0.84 | POLB (0.49) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29898221 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL28857607 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL28857641 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4ELMNAHTTPOLB | |
| SCHEMBL28857590 | 0.82 | POLB (0.51) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |