Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857659 | 0.88 | POLB (0.50) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL28857580 | 0.88 | LMNA (0.66) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL28857581 | 0.85 | LMNA (0.48) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL29898240 | 0.85 | LMNA (0.48) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL28857641 | 0.84 | SMN1; SMN2 (0.51) | LMNAPOLBSMN1; SMN2KDM4EHTT | |
| SCHEMBL28857607 | 0.81 | SMN1; SMN2 (0.46) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL29898221 | 0.81 | SMN1; SMN2 (0.46) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL28857598 | 0.81 | POLB (0.44) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL28857612 | 0.80 | GAA (0.57) | LMNAPOLBMEN1TSHRKMT2A | |
| SCHEMBL28857600 | 0.79 | POLB (0.78) | LMNAPOLBMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |