Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 3/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857620 | 0.88 | TNIK (0.49) | TNIKHTTLMNAPOLB | |
| SCHEMBL28857603 | 0.82 | MEN1 (0.45) | TNIKNOTUMLMNAPOLB | |
| SCHEMBL28857648 | 0.82 | HDAC3 (0.46) | POLB | |
| SCHEMBL28857617 | 0.82 | ESR1 (0.43) | NOTUMHTTLMNAPOLB | |
| SCHEMBL29898258 | 0.81 | POLB (0.49) | HTTLMNAPOLB | |
| SCHEMBL28857616 | 0.81 | POLB (0.49) | HTTLMNAPOLB | |
| SCHEMBL29898221 | 0.80 | SMN1; SMN2 (0.46) | HTTLMNAPOLB | |
| SCHEMBL28857607 | 0.80 | SMN1; SMN2 (0.46) | HTTLMNAPOLB | |
| SCHEMBL28857639 | 0.79 | HTT (0.53) | HTTLMNAPOLB | |
| SCHEMBL28857641 | 0.79 | SMN1; SMN2 (0.51) | HTTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |