Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28857625 | 0.90 | LMNA (0.81) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857636 | 0.90 | LMNA (0.81) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857600 | 0.88 | POLB (0.78) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857613 | 0.88 | LMNA (0.78) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857638 | 0.87 | LMNA (0.77) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857596 | 0.87 | LMNA (0.77) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857594 | 0.86 | LMNA (0.76) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857601 | 0.86 | LMNA (0.79) | LMNAPOLBKDM4EHIF1AEPAS1 | |
| SCHEMBL28857604 | 0.84 | LMNA (0.72) | LMNAPOLBKMT2AHTTMEN1 | |
| SCHEMBL27843308 | 0.81 | LMNA (0.68) | LMNAPOLBKDM4EHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |