Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31112219 | 0.99 | HTT (0.97) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL29898202 | 0.87 | HTT (0.78) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL31112199 | 0.86 | HTT (0.76) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL28955071 | 0.85 | HTT (0.74) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL28857649 | 0.82 | LMNA (0.78) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL28857637 | 0.79 | KDM4E (0.71) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL28857579 | 0.79 | LMNA (0.70) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL28857601 | 0.78 | LMNA (0.79) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL28857594 | 0.78 | LMNA (0.76) | HTTKDM4EKMT2ALMNAPOLB | |
| SCHEMBL28857582 | 0.78 | LMNA (0.68) | HTTKDM4EKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160269-A | Arylcarboxamide derivatives as positive allosteric modulators of NMDAR | 北京大学 | 2022-10-11 | — | — | CN | disclosed |