Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241842 | 0.90 | KDM4E (0.62) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL31056336 | 0.88 | KMT2A (0.50) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL3229895 | 0.88 | KDM4E (0.60) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL8506243 | 0.88 | TDP1 (0.52) | KMT2ATDP1ALDH1A1MAPTMRGPRX4 | |
| SCHEMBL1458413 | 0.87 | LMNA (0.74) | KMT2ALMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL1457712 | 0.86 | MEN1 (0.63) | KMT2ALMNAKDM4EHPGDRAB9A | |
| SCHEMBL4901522 | 0.84 | GLRA1 (0.65) | KMT2ALMNAKDM4EHPGDALDH1A1 | |
| SCHEMBL4311512 | 0.83 | TDP1 (0.62) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL22015355 | 0.83 | LMNA (0.78) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL794412 | 0.83 | KMT2A (0.62) | KMT2ATDP1SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160314-B | Heterocyclic aromatic amide compound and preparation method and application thereof | 南方医科大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-115160314-A | Heterocyclic aromatic amide compound and preparation method and application thereof | 南方医科大学 | 2022-10-11 | — | — | CN | disclosed |