SCHEMBL28857728

SCHEMBL28857728

N[C@H]1CCCC[C@H]1NC(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
GAA P10253 1/20 0.59
CPB1 P15086 2/20 0.57
TSHR P16473 1/20 0.56
EPHX1 P07099 1/20 0.56
CASP3 P42574 3/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
KDM1A O60341 2/20 0.51
MAOA P21397 2/20 0.51
MAOB P27338 2/20 0.51
CTSL P07711 1/20 0.51
CTSB P07858 1/20 0.51
CTSS P25774 1/20 0.51
CTSK P43235 1/20 0.51
RCOR1 Q9UKL0 1/20 0.50
DPP4 P27487 1/20 0.49
KCNH2 Q12809 1/20 0.49
DPP7 Q9UHL4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008551 1.00 ALDH1A1 (0.59) ALDH1A1GAACPB1TSHREPHX1
Hydrochloric Acid SCHEMBL28377105 0.99 ALDH1A1 (0.58) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL12649311 0.97 ALDH1A1 (0.59) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL1766138 0.97 ALDH1A1 (0.59) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL1766151 0.97 ALDH1A1 (0.59) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL1766163 0.97 ALDH1A1 (0.59) ALDH1A1GAACPB1TSHREPHX1
Trifluoroacetic Acid SCHEMBL4425945 0.93 ALDH1A1 (0.52) ALDH1A1GAACPB1TSHREPHX1
Trifluoroacetic Acid SCHEMBL5029718 0.93 ALDH1A1 (0.52) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL6612597 0.90 EPHX1 (0.63) ALDH1A1GAACPB1TSHREPHX1
SCHEMBL6200837 0.84 CASP3 (0.62) ALDH1A1GAACPB1TSHREPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028553-B Preparation method of chiral N-Boc/Cbz-cis- (1R, 2S) -cyclohexanediamine 上海瀚鸿科技股份有限公司 2024-03-26 CN disclosed
CN-115028553-A Preparation method of chiral N-Boc/Cbz-cis- (1R,2S) -cyclohexanediamine 上海瀚鸿科技股份有限公司 2022-09-09 CN disclosed