SCHEMBL28857802

SCHEMBL28857802

Nc1ccccc1Nc1cccc(Br)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 2/20 0.47
MAPT P10636 7/20 0.46
GAA P10253 7/20 0.46
KMT2A Q03164 7/20 0.46
MEN1 O00255 6/20 0.46
KDM4E B2RXH2 5/20 0.46
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KDM1A O60341 1/20 0.45
KDR P35968 1/20 0.44
PIM1 P11309 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
TP53 P04637 1/20 0.43
APP P05067 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16747866 0.79 KMT2A (0.54) MAPK10MAPTGAAKMT2AMEN1
SCHEMBL2779777 0.79 MEN1 (0.50) MAPK10MAPTGAAKMT2AMEN1
SCHEMBL14127502 0.78 KDR (0.51) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL31143287 0.78 KDR (0.51) MAPTKMT2AMEN1KDM4EALDH1A1
SCHEMBL2647288 0.76 MEN1 (0.38) MAPK10MAPTGAAKMT2AMEN1
SCHEMBL28678507 0.75 MAPT (0.45) MAPK10MAPTGAAKMT2AMEN1
SCHEMBL26140602 0.73 MAPT (0.72) MAPTGAAKMT2AMEN1KDM4E
SCHEMBL28857804 0.72 MAPK1 (0.53) MAPTGAAKMT2AMEN1KDM4E
SCHEMBL4943709 0.72 MEN1 (0.73) MAPK10MAPTGAAKMT2AMEN1
SCHEMBL2657596 0.72 GAA (0.47) MAPTGAAKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606582-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-04-21 US disclosed
US-20220298192-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 US disclosed
CN-115028664-A Organic electroluminescent material and device 环球展览公司 2022-09-09 CN disclosed
EP-4053137-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220298192-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, CD79B MAPK10 1700/4885MAPT 3269/4885GAA 3080/4885
US-12606582-B2 Organic electroluminescent materials and devices GLRB, LIFR, LBR MAPK10 2313/4885MAPT 4496/4885GAA 3311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.