SCHEMBL28857804

SCHEMBL28857804

O=[N+]([O-])c1ccccc1Nc1cccc(Br)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.53
ALDH1A1 P00352 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CASP7 P55210 1/20 0.53
MAPT P10636 4/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
RAB9A P51151 1/20 0.51
GAA P10253 1/20 0.48
PKM P14618 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.45
NPC1 O15118 2/20 0.45
EPAS1 Q99814 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4945790 0.82 MAPT (0.58) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL2645906 0.79 MAPK1 (0.50) MAPK1ALDH1A1L3MBTL1MAPTMEN1
SCHEMBL28672316 0.78 MAPT (0.54) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL4810409 0.76 MEN1 (0.71) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL29744982 0.76 MEN1 (0.71) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL2657924 0.76 AKR1C4 (0.51) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL397773 0.76 MAPK1 (0.77) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL9995235 0.75 KMT2A (0.61) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL30677987 0.74 MAPK1 (0.64) MAPK1ALDH1A1TDP1L3MBTL1CASP7
SCHEMBL22188151 0.74 MAPK1 (0.64) MAPK1ALDH1A1TDP1L3MBTL1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606582-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-04-21 US disclosed
US-20220298192-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 US disclosed
CN-115028664-A Organic electroluminescent material and device 环球展览公司 2022-09-09 CN disclosed
EP-4053137-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220298192-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, CD79B MAPK1 1466/4885ALDH1A1 469/4885TDP1 4572/4885
US-12606582-B2 Organic electroluminescent materials and devices GLRB, LIFR, LBR MAPK1 2504/4885ALDH1A1 1641/4885TDP1 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.