Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29744982 | 1.00 | MEN1 (0.71) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL16038460 | 0.84 | ALDH1A1 (0.67) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL7778637 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL6951149 | 0.83 | MAPK1 (0.61) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL19062115 | 0.82 | MEN1 (0.61) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL4929418 | 0.82 | MEN1 (0.61) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11900688 | 0.82 | MEN1 (0.61) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL6832746 | 0.82 | MEN1 (0.61) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL31220843 | 0.82 | MEN1 (0.73) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL31220848 | 0.82 | MEN1 (0.73) | MEN1KMT2ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | claimed |
| US-20060005323-A1 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | claimed |
| CN-118993822-A | Method for green synthesis of aryl nitrifier by using cheap cobalt salt as catalyst | 广东石油化工学院 | 2024-11-22 | — | — | CN | disclosed |
| CN-117088808-A | Antifungal compound and application thereof | 中国人民解放军海军军医大学 | 2023-11-21 | — | — | CN | disclosed |
| US-20080207659-A1 | INHIBITORS OF PHOSPHODIESTERASE TYPE 4 | RANBAXY LABORATORIES LIMITED (IN) | 2008-08-28 | — | — | US | disclosed |
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
| US-7329288-B2 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | disclosed |
| US-20060005323-A1 | N-heteroaryl secondary para-phenylenediamine, a dye composition comprising such a para-phenylenediamine, a process for preparing this composition and use thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
| EP-1568694-A1 | N-heteroaryl-para-phenylene diamines for colouring hair | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207659-A1 | INHIBITORS OF PHOSPHODIESTERASE TYPE 4 | PDE4A, PDE4B, PDE4C | MEN1 4784/4885KMT2A 4487/4885NPC1 4154/4885 |
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | SLC6A4, SLC6A2, SLC6A3 | MEN1 4156/4885KMT2A 1555/4885NPC1 2927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.