Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748345 | 1.00 | HRH3 (0.36) | HRH3HRH2HRH1HRH4CARM1 | |
| SCHEMBL28190250 | 1.00 | HRH3 (0.36) | HRH3HRH2HRH1HRH4CARM1 | |
| SCHEMBL28165088 | 0.89 | L3MBTL1 (0.39) | ALDH1A1PKMDDR1BCHE | |
| SCHEMBL28199801 | 0.89 | L3MBTL1 (0.39) | ALDH1A1PKMDDR1BCHE | |
| SCHEMBL27861727 | 0.88 | CARM1 (0.34) | CARM1PRMT6ALDH1A1PKMPRMT1 | |
| SCHEMBL27353549 | 0.85 | LTA4H (0.35) | HRH3HRH2HRH1HRH4CARM1 | |
| SCHEMBL28157937 | 0.83 | — | — | |
| SCHEMBL28853888 | 0.81 | ADORA2A (0.36) | BCHEACHEBACE1 | |
| SCHEMBL16103858 | 0.79 | L3MBTL1 (0.38) | ALDH1A1BACE1 | |
| SCHEMBL1008457 | 0.79 | POLB (0.46) | HRH3HRH2HRH1HRH4CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-A | 3 tetrazole radical benzene, 1,2 disulfonic acid amide derivative as metal beta lactamase restrainer | 默沙东公司 | 2018-04-17 | — | — | CN | disclosed |