SCHEMBL28858504

SCHEMBL28858504

ClC(CI)c1ccc(Br)cc1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.39
CYP2A6 P11509 1/20 0.38
GSK3B P49841 1/20 0.35
CYP1A2 P05177 1/20 0.33
PYCR1 P32322 1/20 0.32
KMT2A Q03164 1/20 0.32
ABL1 P00519 2/20 0.31
SRC P12931 2/20 0.31
IGF1R P08069 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28858471 0.78 TSHR (0.48) CYP2A6CYP1A2MAPK1
SCHEMBL28858474 0.78 HTR2A (0.40) HTR2ACYP2A6CYP1A2PYCR1KMT2A
SCHEMBL28858569 0.78 HTR2A (0.40) HTR2ACYP2A6GSK3BCYP1A2PYCR1
SCHEMBL11775209 0.75 TSHR (0.50) HTR2AALDH1A1ALOX15
SCHEMBL8465864 0.74 HTR2A (0.38) HTR2ACYP2A6CYP1A2PYCR1KMT2A
SCHEMBL3838715 0.74 HTR2A (0.38) HTR2ACYP2A6GSK3BCYP1A2PYCR1
SCHEMBL4422682 0.73 HTR2A (0.36) HTR2ACYP2A6CYP1A2KMT2A
SCHEMBL537301 0.73 HTR2A (0.36) HTR2ACYP2A6CYP1A2PYCR1KMT2A
SCHEMBL6683976 0.73 PYCR1 (0.38) HTR2ACYP2A6CYP1A2PYCR1KMT2A
SCHEMBL11403776 0.71 IGF1R (0.45) HTR2AGSK3BKMT2AIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197046-B Halogenation method of unsaturated hydrocarbon 华南理工大学 2023-12-15 CN disclosed
CN-115197046-A Halogenation method of unsaturated hydrocarbon 华南理工大学 2022-10-18 CN disclosed