SCHEMBL6683976

SCHEMBL6683976

CCCC(Cl)c1ccc(Br)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.38
KMT2A Q03164 2/20 0.38
HTR2A P28223 1/20 0.36
FPR2 P25090 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CYP1A2 P05177 2/20 0.35
ALOX5 P09917 1/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP2A6 P11509 1/20 0.35
MEN1 O00255 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27647959 0.88 CYP1A2 (0.37) PYCR1HTR2AFPR2CYP1A2ALOX5
SCHEMBL22798698 0.81 CYP2A6 (0.39) KMT2AHTR2ASLC6A2SLC6A4SLC6A3
SCHEMBL9397854 0.80 CHRNA7 (0.38) SLC6A2SLC6A4SLC6A3ALOX5ALDH1A1
SCHEMBL6679840 0.80 TSHR (0.44) SLC6A2SLC6A4SLC6A3HPGDCYP2A6
SCHEMBL3838715 0.80 HTR2A (0.38) PYCR1KMT2AHTR2ACYP1A2ALOX5
SCHEMBL537301 0.78 HTR2A (0.36) PYCR1KMT2AHTR2ACYP1A2ALOX5
SCHEMBL7432877 0.78 ESR1 (0.53) SLC6A2SLC6A3CYP1A2ALDH1A1CYP3A4
SCHEMBL6224183 0.78 ALDH1A1 (0.40) KMT2ASLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL7979678 0.77 HTR2A (0.48) PYCR1KMT2AHTR2AFPR2SLC6A2
SCHEMBL19901495 0.77 ESR1 (0.47) PYCR1KMT2AHTR2AFPR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed