Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365729 | 0.88 | PTPN11 (0.68) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL69025 | 0.88 | PTPN11 (0.68) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL8732524 | 0.86 | PTPN11 (0.66) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL2312019 | 0.85 | KDM4E (0.50) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL9979782 | 0.84 | PTPN11 (0.64) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL17288796 | 0.83 | PTPN11 (0.58) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL709231 | 0.82 | LCK (0.62) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL264052 | 0.81 | PTPN11 (0.60) | PTPN11LCKMAPTKDM4EMEN1 | |
| SCHEMBL13900228 | 0.81 | CYP11B1 (0.69) | PTPN11LCKMAPTKDM4EHTT | |
| SCHEMBL1003761 | 0.81 | KDM4E (0.62) | PTPN11LCKKDM4EHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160098-B | Oxygen-containing compound deoxidization methylation method | 中国科学院兰州化学物理研究所 | 2023-06-06 | — | — | CN | disclosed |
| CN-115160098-A | Oxygen-containing compound deoxidation and methylation method | 中国科学院兰州化学物理研究所 | 2022-10-11 | — | — | CN | disclosed |