Kuromanin

Kuromanin

SCHEMBL288591

OC[C@H]1OC(Oc2cc3c(O)cc(O)cc3[o+]c2-c2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD38 P28907 2/20 1.00
DPP4 P27487 2/20 1.00
F2 P00734 2/20 0.89
KDM4E B2RXH2 4/20 0.52
GAA P10253 4/20 0.52
AKR1B1 P15121 4/20 0.52
MAPT P10636 3/20 0.52
POLB P06746 2/20 0.52
P4HB P07237 2/20 0.52
EPHX2 P34913 2/20 0.52
ADRA2C P18825 1/20 0.52
NOX4 Q9NPH5 1/20 0.52
CA12 O43570 1/20 0.52
KDM1A O60341 1/20 0.52
SLCO2B1 O94956 1/20 0.52
CA2 P00918 1/20 0.52
ALPL P05186 1/20 0.52
HMGB1 P09429 1/20 0.52
ALPI P09923 1/20 0.52
PKM P14618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kuromanin SCHEMBL9234361 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL30548128 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL29349861 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL1101355 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL8818180 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL289710 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL409593 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL1097555 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL1096430 1.00 CD38 (1.00) CD38DPP4F2KDM4EGAA
Kuromanin SCHEMBL440823 0.99 DPP4 (0.98) CD38DPP4F2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3200 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075559-A Portulaca oleracea extract based on bioaffinity ultrafiltration screening and preparation method and application thereof 2026-05-26 CN claimed
CN-121156249-B Nanometer core-shell particle and preparation method and application thereof 武汉理工大学 2026-05-15 CN claimed
US-20260124225-A1 THERAPEUTIC COMPOSITIONS AND METHODS FOR USING SAME KARNICK WILLIAM (US) 2026-05-07 US claimed
EP-4735618-A1 CELL FREE PRODUCTION OF ANTHOCYANINS Debut Biotechnology, Inc. (US) 2026-05-06 EP claimed
WO-2026087503-A1 NON-THERAPEUTIC USE OF ARONIA EXTRACT FOR ENHANCING EXECUTIVE FUNCTION BIOACTOR BV (NL) 2026-04-30 WO claimed
CN-121569946-A Sweet taste enhancing and taste improving composition based on procyanidine B2 and procyanidine-3-O-glucoside 陕西师范大学 2026-02-27 CN claimed
CN-121575070-A Collagen peptide of flower gum, preparation method and application in functional beverage 四川旅游学院 2026-02-27 CN claimed
US-20260027014-A1 DEVICES AND METHODS RELATED TO COLORIMETRIC DETECTION FOR DENTAL USES CAVISENSE INC (US) 2026-01-29 US claimed
US-12507720-B2 Use of anthocyanin-anionic polysaccharide complex for preventing or treating influenza virus A infection JBKLAB CO., LTD. (KR) 2025-12-30 US claimed
US-20250351836-A1 SEED EXTRACT FOR USE DURING FOOD COOKING AND STORAGE PROCESSES Khalifa University of Science and Technology (AE) 2025-11-20 US claimed
WO-2002017945-A1 EFFICIENT METHOD FOR PRODUCING COMPOSITIONS ENRICHED IN ANTHOCYANINS HAUSER, INC. (US) 2002-03-07 WO claimed
EP-0792588-B1 Fruit drink ECKES GRANINI GMBH CO KG (DE) 2001-12-12 EP claimed
US-20010047032-A1 Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases PROTAMED, INC. 2001-11-29 US claimed
WO-2001080870-A2 COMPOSITIONS DERIVED FROM CRANBERRY AND GRAPEFRUIT AND THERAPEUTIC USES THEREFOR OCEAN SPRAY CRANBERRIES, INC. (US) 2001-11-01 WO claimed
WO-2001052809-A1 COSMETIC AND/OR PHARMACEUTICAL PREPARATIONS CONTAINING AN ACTIVE QUANTITY OF AN ARRABIDAEA CHICA EXTRACT COGNIS FRANCE, S.A. (FR) 2001-07-26 WO claimed
WO-2001049281-A2 POLYHYDROXYLATED AROMATIC COMPOUNDS FOR THE TREATMENT OF AMYLOIDOSIS AND α-SYNUCLEIN FIBRIL DISEASES PROTEOTECH, INC. (US) 2001-07-12 WO claimed
US-6194469-B1 INHIBITING CYCLOOXYGENASE OR PROSTOGLANDIN H SYNTHASE ENZYMES BY PROVIDING AN ANTHOCYANIN ISOLATED FROM CHERRY FRUIT SELECTED FROM CYANIDIN-3-GLUCOSYLRUTINOSIDE, CYANIDIN-3-RUTINOSIDE OR CYANIDIN-3-GLUCOSIDE BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERISTY 2001-02-27 US claimed
WO-2000064282-B1 NUTRACEUTICALS AND INGREDIENTS FOR FUNCTIONAL FOODS TORTORA DIOMEDE ANTONIO (IT) 2001-01-25 WO claimed
WO-1998038316-A1 BETA-GLUCOSIDASES, METHODS FOR OBTAINING SAME, PREPARATIONS CONTAINING SAID BETA-GLUCOSIDASES AND USES THEREOF DSM N.V. (NL) 1998-09-03 WO claimed
EP-0792588-A1 Fruit drink Eckes-Granini GmbH & Co. Kommanditgesellschaft (DE) 1997-09-03 EP claimed