Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | RELA | Q04206 | 2/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892848 | 0.87 | CYP1A2 (0.36) | L3MBTL1MEN1KMT2AABL1CYP1A2 | |
| SCHEMBL2885936 | 0.86 | NPC1 (0.31) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2893543 | 0.85 | LMNA (0.36) | L3MBTL1KMT2ALMNA | |
| SCHEMBL2890314 | 0.85 | POLB (0.44) | RAB9ASMN1; SMN2L3MBTL1KDM4EMEN1 | |
| SCHEMBL2893101 | 0.74 | CYP1A2 (0.35) | L3MBTL1MEN1KMT2AABL1CYP1A2 | |
| SCHEMBL7981790 | 0.73 | — | — | |
| SCHEMBL2885774 | 0.71 | POLB (0.44) | SMN1; SMN2L3MBTL1KDM4EMEN1MAPT | |
| SCHEMBL2891653 | 0.71 | LMNA (0.36) | KMT2ALMNA | |
| SCHEMBL21753345 | 0.70 | CYP11B1 (0.47) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL5306346 | 0.70 | IDO1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | claimed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | claimed |
| EP-2227458-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL-THIAZOL-DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2010-09-15 | — | — | EP | claimed |
| WO-2009068170-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL THIAZOLE DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | WO | claimed |
| US-8754234-B2 | Chiral 2-(benzylsulfinyl)thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2014-06-17 | — | — | US | disclosed |
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| EP-2227458-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL-THIAZOL-DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068170-A2 | 2-(BENZYL- AND 1H-PYRAZOL-4-YLMETHYL)SULFINYL THIAZOLE DERIVATIVES AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100285958-A1 | Chiral 2-(benzylsulfinyl)Thiazole derivatives and 2-[(1H-pyrazol-4-ylmethyl)sulfinyl]thiazole derivatives, processes for their preparation and their use as herbicides and plant growth regulators | STS, SULT2A1, SLTM | NPC1 4791/4885RAB9A 3579/4885SMN1; SMN2 4145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.