Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811339 | 0.78 | TPMT (0.52) | SLC7A5NPC1RAB9ATPMTTDP1 | |
| SCHEMBL21574901 | 0.78 | PARP10 (0.44) | SLC7A5GRIN2BNPC1RAB9ATPMT | |
| SCHEMBL24080830 | 0.74 | PGK1 (0.43) | GRIN2BRAB9APGK1PGK2 | |
| SCHEMBL28947533 | 0.70 | TSHR (0.46) | SLC7A5NPC1RAB9ATPMTTDP1 | |
| SCHEMBL28848239 | 0.70 | MAPT (0.36) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL16405265 | 0.68 | SLC7A5 (0.51) | SLC7A5TDP1CA12CA1CA2 | |
| SCHEMBL27775516 | 0.67 | CA12 (0.39) | SLC7A5MRGPRX4TDP1CA12CA1 | |
| SCHEMBL16769676 | 0.67 | CA12 (0.58) | SLC7A5NPC1CA12CA1CA2 | |
| SCHEMBL14143757 | 0.67 | SLC7A5 (0.62) | SLC7A5TDP1CA12CA1CA2 | |
| SCHEMBL2161045 | 0.67 | SLC7A5 (0.62) | SLC7A5TDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379575-B | Compounds and compositions for modulating EGFR activity | 诺华股份有限公司 | 2018-04-17 | — | — | CN | disclosed |