Piperic Acid

Piperic Acid

SCHEMBL288595

O=C(O)C=CC=Cc1ccc2c(c1)OCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 1.00
CYP1A2 P05177 2/20 1.00
HDAC6 Q9UBN7 2/20 0.72
MAOB P27338 3/20 0.69
GABRA1 P14867 4/20 0.65
GABRB2 P47870 4/20 0.65
KDM4E B2RXH2 3/20 0.65
TRPV1 Q8NER1 3/20 0.65
ALDH1A1 P00352 2/20 0.65
CYP3A4 P08684 2/20 0.65
HPGD P15428 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
MAOA P21397 2/20 0.65
NPC1 O15118 1/20 0.65
CTSD P07339 1/20 0.65
ABCB1 P08183 1/20 0.65
ALOX5 P09917 1/20 0.65
MAPK1 P28482 1/20 0.65
RAB9A P51151 1/20 0.65
DHODH Q02127 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperic Acid SCHEMBL447578 1.00 HSD17B10 (1.00) HSD17B10CYP1A2HDAC6MAOBGABRA1
Piperic Acid SCHEMBL29429112 1.00 HSD17B10 (1.00) HSD17B10CYP1A2HDAC6MAOBGABRA1
Piperic Acid SCHEMBL11460093 1.00 HSD17B10 (1.00) HSD17B10CYP1A2HDAC6MAOBGABRA1
Piperic Acid SCHEMBL11460092 1.00 HSD17B10 (1.00) HSD17B10CYP1A2HDAC6MAOBGABRA1
Piperic Acid SCHEMBL28765417 0.98 HSD17B10 (0.97) HSD17B10CYP1A2HDAC6MAOBGABRA1
Piperic Acid SCHEMBL11500707 0.93 HSD17B10 (0.86) HSD17B10CYP1A2HDAC6MAOBGABRA1
Piperic Acid SCHEMBL11500706 0.93 HSD17B10 (0.86) HSD17B10CYP1A2HDAC6MAOBGABRA1
SCHEMBL3106338 0.91 HSD17B10 (0.83) HSD17B10CYP1A2HDAC6MAOBGABRA1
SCHEMBL3106343 0.91 HSD17B10 (0.83) HSD17B10CYP1A2HDAC6MAOBGABRA1
Piperic Acid SCHEMBL11479454 0.91 HSD17B10 (0.82) HSD17B10CYP1A2HDAC6MAOBGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 940 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12593844-B2 Method and compounds to induce plant tolerance against arthropod pests VIB VZW (BE) 2026-04-07 US claimed
CN-118104665-B Insecticidal and bactericidal composition and application thereof 沈阳中化农药化工研发有限公司 2025-06-24 CN claimed
CN-118058286-B Pesticide preparation containing piperic acid derivative 沈阳中化农药化工研发有限公司 2025-05-16 CN claimed
CN-118104669-B Synergistic compound composition of two active components and application thereof 沈阳中化农药化工研发有限公司 2025-05-13 CN claimed
CN-118216508-B Compound mosquito-killing larva composition and application thereof 江苏扬农化工股份有限公司 2025-04-29 CN claimed
CN-118104662-B Binary insecticidal synergistic composition and application thereof 沈阳中化农药化工研发有限公司 2025-03-28 CN claimed
CN-119563630-A Composition containing biological insecticide and application thereof 沈阳中化农药化工研发有限公司 2025-03-07 CN claimed
CN-118216509-B Retention spraying insecticidal composition containing piperic acid derivative compounds 江苏扬农化工股份有限公司 2025-02-28 CN claimed
CN-118104666-B Synergistic compound composition containing spiro tetronic acid type insecticidal and acaricidal agents and application thereof 沈阳中化农药化工研发有限公司 2025-02-11 CN claimed
CN-118216507-B Space spraying insecticidal composition containing piperic acid derivative compounds 江苏扬农化工股份有限公司 2025-02-11 CN claimed
WO-2006048671-A1 POLYAMINE COMPOSITIONS BIOFORSKNING AS (NO) 2006-05-11 WO claimed
WO-2006040016-A1 FUNGICIDAL COMBINATIONS OF ACTIVE INGREDIENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2006-04-20 WO claimed
WO-2006008108-A2 SELECTIVE INSECTICIDES BASED ON HALOALKYLNICOTINIC ACID DERIVATIVES, ANTHRANILIC ACID DIAMIDES, OR PHTHALIC ACID DIAMIDES AND SAFENERS BAYER CROPSCIENCE AG (DE) 2006-01-26 WO claimed
CN-1634030-A Use of piperic acid ester compound in preparation of drug or healthcare product for reducing blood fat UNIV INNER MONGOLIA (CN) 2005-07-06 CN claimed
EP-1303189-A1 ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES Bayer CropScience AG (DE) 2003-04-23 EP claimed
WO-2002001957-A1 ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES BAYER CROPSCIENCE AG (DE) 2002-01-10 WO claimed
CN-1298936-A Process for preparing health-care peperic acid wine LI YUETING (CN) 2001-06-13 CN claimed
US-5763535-A Process for production of a powder coating KANSAI PAINT CO., LTD. (JP) 1998-06-09 US claimed
US-5631054-A DIPHENOLIC ADDITIVE; STRETCH BLOW MOLDING KAO CORPORATION (JP) 1997-05-20 US claimed
WO-1993023061-A1 THERAPEUTIC USES OF PUNGENT BOTANICALS AND THEIR RELATED COMPOUNDS STAGGS JEFF J (US) 1993-11-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12593844-B2 Method and compounds to induce plant tolerance against arthropod pests HPD, PAH, P4HTM HSD17B10 681/4885CYP1A2 754/4885HDAC6 2785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.