Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106343 | 1.00 | HSD17B10 (0.83) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| Piperic Acid SCHEMBL11460093 | 0.91 | HSD17B10 (1.00) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| Piperic Acid SCHEMBL11460092 | 0.91 | HSD17B10 (1.00) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| Piperic Acid SCHEMBL447578 | 0.91 | HSD17B10 (1.00) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| Piperic Acid SCHEMBL29429112 | 0.91 | HSD17B10 (1.00) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| Piperic Acid SCHEMBL288595 | 0.91 | HSD17B10 (1.00) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| Piperic Acid SCHEMBL28765417 | 0.89 | HSD17B10 (0.97) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| SCHEMBL2730205 | 0.89 | KDM4E (1.00) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| SCHEMBL2730201 | 0.89 | KDM4E (1.00) | HSD17B10CYP1A2KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28538962 | 0.87 | KDM4E (0.97) | HSD17B10CYP1A2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2194044-A1 | QUINOLONE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-20060094874-A1 | Novel substituted aryl alkenoic acid heterocyclic amides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094874-A1 | Novel substituted aryl alkenoic acid heterocyclic amides | FABP1, LIPC, FABP2 | HSD17B10 169/4885CYP1A2 70/4885KDM4E 1636/4885 |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | HSD17B10 164/4885CYP1A2 154/4885KDM4E 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.