Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | RGS4 | P49798 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25435490 | 0.70 | MGLL (1.00) | MGLLGSK3AGSK3BELANEF2 | |
| SCHEMBL207740 | 0.70 | MGLL (1.00) | MGLLGSK3AGSK3BELANEF2 | |
| SCHEMBL10430467 | 0.69 | HPGD (0.46) | MGLLGSK3AGSK3BELANEF2 | |
| SCHEMBL1078286 | 0.69 | SIGMAR1 (0.48) | MGLLGSK3AGSK3BELANEF2 | |
| SCHEMBL11052192 | 0.68 | KMT2A (0.59) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL27477427 | 0.68 | HPGD (0.49) | MGLLGSK3AGSK3BELANEF2 | |
| SCHEMBL8985073 | 0.66 | GSK3B (0.67) | MGLLGSK3AGSK3BELANEF2 | |
| SCHEMBL13793073 | 0.66 | ELANE (0.82) | MGLLGSK3AGSK3BELANEF2 | |
| Hydrochloric Acid SCHEMBL29906145 | 0.65 | GSK3A (0.37) | MGLLGSK3AGSK3BELANEF2 | |
| SCHEMBL26113746 | 0.65 | PARP1 (0.49) | MGLLGSK3AGSK3BELANEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108033969-A | A kind of Oxoindole spiral shell tetrahydrofuran-compound and its preparation method and application | 中国医药集团总公司四川抗菌素工业研究所 | 2018-05-15 | — | — | CN | claimed |