Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.55 |
| ▸ | NOS2 | P35228 | 2/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | TDO2 | P48775 | 3/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PRKACA | P17612 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Aminopyridine SCHEMBL9064720 | 0.74 | NOS3 (1.00) | NOS3NOS2NOS1PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL29392931 | 0.74 | — | — | |
| 2-Aminopyridine SCHEMBL2775240 | 0.74 | — | — | |
| 2-Aminopyridine SCHEMBL17844 | 0.74 | — | — | |
| 2-Aminopyridine SCHEMBL15012466 | 0.72 | — | — | |
| 2-Aminopyridine SCHEMBL8135890 | 0.72 | NOS3 (0.94) | NOS3NOS2NOS1PI4KAPI4K2B | |
| 2-Aminopyridine SCHEMBL2333406 | 0.72 | — | — | |
| 2-Aminopyridine SCHEMBL70318 | 0.72 | — | — | |
| 2-Aminopyridine SCHEMBL20496124 | 0.72 | — | — | |
| 2-Aminopyridine SCHEMBL4938381 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104244944-B | For treating the compound of spinal muscular atrophy | PTC医疗公司 | 2018-06-08 | — | — | CN | disclosed |