Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28181566 | 0.91 | LMNA (0.33) | LMNAMMP8PTPN1TSHR | |
| SCHEMBL6063663 | 0.88 | LMNA (0.41) | LMNAPTPN1TSHRMEN1KMT2A | |
| SCHEMBL236285 | 0.86 | TSHR (0.40) | LMNAMMP8PTPN1TSHRMEN1 | |
| SCHEMBL28167346 | 0.82 | MMP8 (0.40) | LMNAMMP8TSHR | |
| SCHEMBL31462323 | 0.82 | LMNA (0.37) | LMNAPTPN1TSHRMEN1KMT2A | |
| SCHEMBL28137704 | 0.81 | MMP8 (0.50) | LMNAMMP8TSHRMEN1KMT2A | |
| SCHEMBL28167334 | 0.79 | MMP8 (0.38) | LMNAMMP8TSHRMEN1KMT2A | |
| SCHEMBL232754 | 0.78 | TSHR (0.37) | LMNAPTPN1TSHRMEN1KMT2A | |
| SCHEMBL28773718 | 0.77 | PTPN1 (0.34) | LMNAPTPN1TSHRMEN1KMT2A | |
| SCHEMBL29220263 | 0.77 | LMNA (0.33) | LMNAPTPN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640886-B | The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization | 东邦钛株式会社 | 2018-04-27 | — | — | CN | disclosed |