Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278459 | 0.88 | HDAC2 (0.71) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2292513 | 0.87 | SERPINE1 (0.62) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL9743979 | 0.87 | MAPT (0.58) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2271280 | 0.86 | ACLY (0.62) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2274304 | 0.85 | ACLY (0.55) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2270444 | 0.85 | MEN1 (0.54) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2276918 | 0.84 | SNCA (0.66) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2271080 | 0.84 | MEN1 (0.56) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2274811 | 0.84 | PYGM (0.57) | KMT2AMEN1PKMGRIK1MAPT | |
| SCHEMBL2276923 | 0.84 | SNCA (0.66) | KMT2AMEN1PKMGRIK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129438-A | A kind of compound of the chroman of benzene containing 2- parent nucleus and preparation method thereof | 中国海洋大学 | 2018-06-08 | — | — | CN | disclosed |