Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161389 | 0.89 | KDM4E (0.42) | MAPTKDM4ERAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9521121 | 0.86 | MAOB (0.40) | MAPTKDM4ERAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9827612 | 0.76 | PSMB5 (0.41) | MAPTKDM4ERAB9ASMN1; SMN2GAA | |
| SCHEMBL23966083 | 0.76 | MAOB (0.40) | KDM4ERAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL22183626 | 0.76 | MAOB (0.40) | KDM4ERAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3964318 | 0.75 | MAOB (0.42) | KDM4ERAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9464905 | 0.74 | MAOB (0.45) | KDM4ERAB9ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL17362278 | 0.72 | MAOA (0.39) | BRD4MAOAMAOBCYP2A6PRKCI | |
| SCHEMBL6301106 | 0.71 | BRD4 (0.52) | MAPTKDM4ERAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL11593637 | 0.70 | NQO2 (0.35) | MAPTKDM4ERAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197906-A1 | Method for purification of chlorinated sucrose derivatives from reaction mixture by chromatography | PHARMED MEDICARE PRIVATE LIMITED (IN) | 2010-08-05 | — | — | US | disclosed |
| WO-2007023505-A2 | METHOD FOR PURIFICATION OF CHLORINATED SUCROSE DERIVATIVES FROM REACTION MIXTURE BY CHROMATOGRAPHY | PHARMED MEDICARE PRIVATE LIMITED (IN) | 2007-03-01 | — | — | WO | disclosed |
| EP-0325963-B1 | 1-AMINOMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENES AND -INDANES | ABBOTT LABORATORIES (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5140040-A | Alpha-2-adrenergic receptor antagonist; glaucoma; congestive heart failure; hypotensive agents; headaches; metabolic disorders (diabetes, obesity) | ABBOTT LABORATORIES (US) | 1992-08-18 | — | — | US | disclosed |
| US-5128362-A | Antidepressant, antiglaucoma | ABBOTT LABORATORIES (US) | 1992-07-07 | — | — | US | disclosed |
| US-5086074-A | Selective adrenergic receptor antagonists | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| EP-0166937-B1 | ADRENERGIC COMPOUNDS | ABBOTT LABORATORIES (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0395734-A4 | 1-AMINOMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENES | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0395734-A1 | 1-AMINOMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENES | ABBOTT LABORATORIES (US) | 1990-11-07 | — | — | EP | disclosed |
| EP-0325963-A1 | 1-Aminomethyl-1,2,3,4-tetrahydronaphthalenes and -indanes | ABBOTT LABORATORIES (US) | 1989-08-02 | — | — | EP | disclosed |
| WO-1989006645-A1 | 1-AMINOMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENES | ABBOTT LABORATORIES (US) | 1989-07-27 | — | — | WO | disclosed |
| US-4634705-A | Adrenergic amidines | ABBOTT LABORATORIES (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0166937-A2 | Adrenergic compounds | ABBOTT LABORATORIES (US) | 1986-01-08 | — | — | EP | disclosed |
| US-4473586-A | Aminoalkyl dihydronaphthalenes | ABBOTT LABORATORIES (US) | 1984-09-25 | — | — | US | disclosed |