SCHEMBL288621

SCHEMBL288621

C=CCC1(C)C(=O)OCOC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8409547 0.78 CPT1A (0.30)
SCHEMBL12669329 0.77
SCHEMBL17960731 0.76 CPT1A (0.33)
SCHEMBL17592799 0.73 KDM4E (0.34)
SCHEMBL666966 0.71 CYP19A1 (0.35)
SCHEMBL15536998 0.70 ALDH1A1 (0.32)
SCHEMBL19973131 0.70 NPSR1 (0.37)
SCHEMBL31384135 0.68 LMNA (0.37)
SCHEMBL16736246 0.67 HSD17B10 (0.38)
SCHEMBL2712113 0.66 TP53 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183170-A1 1,1-DISUBSTITUTED ETHYLENE PROCESS OPTMED, INC. 2023-06-15 US disclosed
US-11555011-B2 1,1-disubstituted ethylene process H.B. FULLER COMPANY (US) 2023-01-17 US disclosed
US-20200223790-A1 IMPROVED 1,1-DISUBSTITUTED ETHYLENE PROCESS OPTMED, INC. (US) 2020-07-16 US disclosed
US-10597355-B2 1,1-disubstituted ethylene process OPTMED, INC. (US) 2020-03-24 US disclosed
EP-2807138-B1 PURIFICATION OF 1, 1-DISUBSTITUTED ETHYLENE COMPOUNDS OPTMED INC (US) 2019-10-16 EP disclosed
EP-2807142-B1 IMPROVED METHYLIDENE MALONATE PROCESS OPTMED INC (US) 2019-09-04 EP disclosed
US-9540309-B2 Methylidene malonate process OPTMED, INC. (US) 2017-01-10 US disclosed
US-9487468-B2 Methylidene malonate process OPTMED, INC. (US) 2016-11-08 US disclosed
US-20150203437-A1 METHYLIDENE MALONATE PROCESS OPTMED INC. (US) 2015-07-23 US disclosed
US-20150183714-A1 METHYLIDENE MALONATE PROCESS OPTMED, INC. (US) 2015-07-02 US disclosed
US-20130012736-A1 METHYLIDENE MALONATE PROCESS OPTMED, INC. (US) 2013-01-10 US disclosed
EP-2427423-A1 IMPROVED METHYLIDENE MALONATE PROCESS Optmed Inc. (US) 2012-03-14 EP disclosed
EP-2427422-A1 IMPROVED METHYLIDENE MALONATE PROCESS Optmed Inc. (US) 2012-03-14 EP disclosed
US-8106234-B2 Methylidene malonate process OptMed, Inc (US) 2012-01-31 US disclosed
US-20100286439-A1 METHYLIDENE MALONATE PROCESS OPTMED, INC. 2010-11-11 US disclosed
US-20100286438-A1 METHYLIDENE MALONATE PROCESS OPTMED, INC. 2010-11-11 US disclosed
US-20100286433-A1 METHYLIDENE MALONATE PROCESS OPTMED, INC. 2010-11-11 US disclosed
WO-2010129066-A1 IMPROVED METHYLIDENE MALONATE PROCESS OPTMED INC. (US) 2010-11-11 WO disclosed
WO-2010129068-A1 IMPROVED METHYLIDENE MALONATE PROCESS OPTMED INC. (US) 2010-11-11 WO disclosed
WO-2010129067-A1 IMPROVED METHYLIDENE MALONATE PROCESS OPTMED INC. (US) 2010-11-11 WO disclosed