Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.53 |
| ▸ | HTR7 | P34969 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19054640 | 0.85 | HTR6 (0.58) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL29429815 | 0.83 | HTR6 (0.56) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL6039811 | 0.83 | HTR6 (0.56) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL15648088 | 0.79 | HTR6 (0.60) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL19054622 | 0.78 | HTR6 (0.53) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL29613438 | 0.78 | EGFR (0.51) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL16665592 | 0.78 | EGFR (0.51) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL17140750 | 0.74 | CYP3A4 (0.48) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL24511089 | 0.74 | HTR6 (0.44) | HTR6DRD2HTR2AHTR7HTR1A | |
| SCHEMBL18340726 | 0.74 | HTR6 (0.53) | HTR6DRD2HTR2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276382-B | Cyclin-dependent kinase inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |