Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665592 | 1.00 | EGFR (0.51) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL15648478 | 0.89 | EGFR (0.47) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL29613463 | 0.87 | CDK7 (0.55) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL15649053 | 0.87 | CDK7 (0.55) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL17141040 | 0.87 | CDK7 (0.48) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL27223018 | 0.86 | EGFR (0.48) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL29613470 | 0.86 | EGFR (0.48) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL30886756 | 0.86 | EGFR (0.48) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL17141301 | 0.84 | CDK7 (0.52) | EGFRCCNT1CCNB2CCNE2CDK1 | |
| SCHEMBL18074097 | 0.84 | CDK7 (0.56) | EGFRCCNT1CCNB2CCNE2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4259133-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |