Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.46 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993908 | 1.00 | HTR6 (0.46) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL29429815 | 0.87 | HTR6 (0.56) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL6039811 | 0.87 | HTR6 (0.56) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL6039808 | 0.81 | HTR6 (0.55) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL16990238 | 0.80 | HTR6 (0.50) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL30725457 | 0.78 | CCNC (0.49) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL29174646 | 0.78 | CCNC (0.49) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL21178276 | 0.77 | HTR6 (0.40) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL30260778 | 0.77 | HTR6 (0.40) | HTR6HTR2AHTR7DRD2HTR1A | |
| SCHEMBL17490483 | 0.76 | PDK1 (0.42) | DRD2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276382-B | Cyclin-dependent kinase inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |