SCHEMBL2886247

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12995683	0.95	TP53 (0.41)	TP53RAB9ASMN1; SMN2MAPTTHRB
	SCHEMBL13051901	0.91	TP53 (0.43)	TP53RAB9ASMN1; SMN2NPC1CYP1A2
	SCHEMBL12995593	0.90	TP53 (0.42)	TP53RAB9ASMN1; SMN2NPC1CYP1A2
	SCHEMBL13151854	0.90	TP53 (0.42)	TP53RAB9ASMN1; SMN2NPC1CYP1A2
	SCHEMBL14468020	0.90	TP53 (0.44)	TP53RAB9ASMN1; SMN2NPC1CYP1A2
	SCHEMBL14467838	0.90	TP53 (0.42)	TP53RAB9ASMN1; SMN2NPC1CYP1A2
	SCHEMBL2886366	0.90	TP53 (0.42)	TP53RAB9ASMN1; SMN2NPC1CYP1A2
	SCHEMBL2884005	0.90	TP53 (0.43)	TP53RAB9ASMN1; SMN2NPC1CYP1A2
	SCHEMBL12995681	0.89	ALDH1A1 (0.42)	TP53RAB9ANPC1HPGDMAPT
	SCHEMBL13052005	0.89	TP53 (0.41)	TP53RAB9ASMN1; SMN2NPC1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.