SCHEMBL28862959

SCHEMBL28862959

O=P(O)(O)Oc1c(O)cc(O)cc1O.[NaH].[NaH]

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 11/20 0.48
INPP5A Q14642 6/20 0.47
AKT1 P31749 1/20 0.46
INPP5B P32019 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
SRC P12931 3/20 0.41
BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5370752 0.98 INPPL1 (0.50) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL8389832 0.84 SRC (0.53) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL4179025 0.81 TDP1 (0.40) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL4186090 0.78 TDP1 (0.38) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL4875733 0.77 TPMT (0.50) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL28786310 0.74 INPPL1 (0.61) INPPL1INPP5AAKT1INPP5BTDP1
SCHEMBL4172258 0.74 INPPL1 (0.61) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL4454764 0.71 INPPL1 (0.71) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL29145019 0.71 INPPL1 (0.42) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL4181314 0.71 INPPL1 (0.60) INPPL1INPP5AAKT1INPP5BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108498492-A A kind of purposes of phloroglucin in preparing the drug for promoting union 广东医科大学 2018-09-07 CN disclosed