SCHEMBL4454764

SCHEMBL4454764

O=P(O)(O)Oc1cc(O)cc(O)c1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 12/20 0.71
INPP5A Q14642 6/20 0.71
SRC P12931 2/20 0.50
INPP5B P32019 2/20 0.50
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
BACE1 P56817 2/20 0.40
BLM P54132 1/20 0.39
AKT1 P31749 1/20 0.39
HSP90AA1 P07900 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4186085 0.84 INPPL1 (1.00) INPPL1INPP5ASRCINPP5BCA1
SCHEMBL4179021 0.82 INPPL1 (0.48) INPPL1INPP5ASRCINPP5BBACE1
SCHEMBL4181918 0.79 INPPL1 (0.45) INPPL1INPP5ASRCINPP5BBACE1
SCHEMBL29743077 0.78 SRC (0.59) INPPL1INPP5ASRCINPP5BCA1
SCHEMBL14176584 0.78 INPPL1 (0.60) INPPL1INPP5ASRCINPP5BCA1
SCHEMBL133534 0.78 SRC (0.59) INPPL1INPP5ASRCINPP5BCA1
SCHEMBL30340348 0.78 PTGS2 (0.60) INPPL1INPP5ASRCCA1CA2
SCHEMBL2193074 0.78 PTGS2 (0.60) INPPL1INPP5ASRCCA1CA2
SCHEMBL4166639 0.76 PTGS2 (0.58) INPPL1INPP5ASRCCA1CA2
SCHEMBL30340032 0.76 PTGS1 (0.58) INPPL1INPP5ASRCCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10877035-B2 Advanced drug development and manufacturing ICAGEN, LLC (US) 2020-12-29 US disclosed
US-20150309021-A1 Advanced Drug Development and Manufacturing LOS ALAMOS NATIONAL SECURITY, LLC 2015-10-29 US disclosed
EP-2511844-B1 X-ray microscope XRPRO SCIENCES INC (US) 2015-08-12 EP disclosed
EP-2511844-A2 Advanced drug development and manufacturing Los Alamos National Security, LLC (US) 2012-10-17 EP disclosed
EP-2084519-B1 X-RAY FLUORESCENCE ANALYSIS METHOD LOS ALAMOS NAT SECURITY LLC (US) 2012-08-01 EP disclosed
EP-2084519-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING Los Alamos National Security, LLC (US) 2009-08-05 EP disclosed
WO-2008127291-A2 ADVANCED DRUG DEVELOPMENT AND MANUFACTURING LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-23 WO disclosed
US-20080220441-A1 Advanced drug development and manufacturing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-09-11 US disclosed
US-7205345-B2 Blend of a styrene resin, phenolic resin and phosphazene compound; heat resistance POLYPLASTICS CO., LTD. (JP) 2007-04-17 US disclosed
US-7169836-B2 Mixture of a phosphazene compound, polyphenylene ether , styrene resin and organonitrogen compound POLYPLASTICS CO., LTD (JP) 2007-01-30 US disclosed
US-20050148701-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2005-07-07 US disclosed
US-20040147646-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-07-29 US disclosed