SCHEMBL4186090

SCHEMBL4186090

O=P(O)(O)OP(=O)(O)OP(=O)(O)Oc1c(O)cc(O)cc1O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
INPPL1 O15357 6/20 0.34
INPP5A Q14642 4/20 0.34
INPP5B P32019 1/20 0.34
BACE1 P56817 1/20 0.34
SRC P12931 2/20 0.33
FDPS P14324 1/20 0.32
BLM P54132 1/20 0.32
AKT1 P31749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4179025 0.96 TDP1 (0.40) TDP1INPPL1INPP5AINPP5BBACE1
SCHEMBL5370752 0.80 INPPL1 (0.50) TDP1INPPL1INPP5AINPP5BBACE1
Triphosphate SCHEMBL4186099 0.80 FDPS (0.45) TDP1INPPL1INPP5AINPP5BBACE1
SCHEMBL4181918 0.79 INPPL1 (0.45) TDP1INPPL1INPP5AINPP5BBACE1
SCHEMBL28862959 0.78 INPPL1 (0.48) TDP1INPPL1INPP5AINPP5BBACE1
SCHEMBL4181363 0.76 FDPS (0.38) TDP1INPPL1INPP5AINPP5BFDPS
SCHEMBL4179021 0.75 INPPL1 (0.48) TDP1INPPL1INPP5AINPP5BBACE1
SCHEMBL4172265 0.72 TDP1 (0.38) TDP1INPPL1INPP5AINPP5BFDPS
SCHEMBL4186933 0.72 TDP1 (0.38) TDP1INPPL1INPP5AINPP5BFDPS
SCHEMBL4186927 0.71 INPPL1 (0.36) TDP1INPPL1INPP5AINPP5BFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US claimed
JP-2008545385-A 2008-12-18 JP claimed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP claimed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO claimed
CN-117222705-A Thermosetting composition, method for producing molded article using same, and cured article 出光兴产株式会社 2023-12-12 CN disclosed
CN-117178003-A Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article 出光兴产株式会社 2023-12-05 CN disclosed
CN-117120494-A Thermosetting composition, method for producing molded article using same, and cured article 出光兴产株式会社 2023-11-24 CN disclosed
CN-117098787-A Thermosetting composition for injection molding, method for producing molded article using the composition, and cured article 出光兴产株式会社 2023-11-21 CN disclosed
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP disclosed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098589-A1 Method ALPL, PPA1, ITPA TDP1 1661/4885INPPL1 40/4885INPP5A 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.