Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241186 | 0.83 | L3MBTL1 (0.53) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL877951 | 0.82 | CYP2C19 (0.53) | LMNAMAPK1 | |
| SCHEMBL28257946 | 0.81 | L3MBTL1 (0.52) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL6203195 | 0.81 | LMNA (0.60) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL21410266 | 0.81 | L3MBTL1 (0.52) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL23849637 | 0.81 | L3MBTL1 (0.52) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28312779 | 0.81 | L3MBTL1 (0.52) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL7580361 | 0.80 | L3MBTL1 (0.59) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL11822391 | 0.80 | LMNA (0.50) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL9066704 | 0.80 | LMNA (0.50) | L3MBTL1TDP1LMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153644-B | Small molecules against CEREBLON to enhance effector T cell function | H·李·莫菲特癌症中心研究有限公司 | 2022-10-21 | — | — | CN | disclosed |