Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrobenzene SCHEMBL28241110 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| P-Nitrophenol SCHEMBL28241113 | 0.82 | GAA (0.45) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL9098377 | 0.78 | MAOB (0.47) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL774134 | 0.78 | CA4 (0.54) | NPC1RAB9A | |
| SCHEMBL8784660 | 0.78 | CA4 (0.54) | NPC1RAB9A | |
| Nitrophenolate SCHEMBL28749822 | 0.76 | GPR35 (0.57) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL30389842 | 0.76 | CA4 (0.52) | ALDH1A1TDP1 | |
| Bromide SCHEMBL31164184 | 0.76 | CA4 (0.52) | NPC1RAB9A | |
| Nitrophenolate SCHEMBL29290800 | 0.74 | GPR35 (0.59) | SMN1; SMN2KMT2AMAPK1HPGDALDH1A1 | |
| Nitrophenolate SCHEMBL29051225 | 0.74 | GPR35 (0.63) | SMN1; SMN2KMT2AMAPTMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610360-A | Phosphoramidite and its preparation method and application | 中国石油大学(华东) | 2018-10-02 | — | — | CN | claimed |