Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.95 |
| ▸ | MEN1 | O00255 | 5/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938460 | 0.87 | KDM4E (0.74) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL20765529 | 0.82 | ALDH1A1 (0.74) | ALDH1A1KDM4EKMT2AMEN1ALOX15 | |
| SCHEMBL3766736 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL3766741 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL28767825 | 0.79 | PTGDR2 (0.70) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL4779980 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL3456878 | 0.79 | EPHX2 (0.71) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL2959924 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL28864301 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL10293591 | 0.77 | MEN1 (0.59) | ALDH1A1KDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197168-A | Preparation method of flumatinib and analogues thereof | 江苏豪森药业集团有限公司 | 2022-10-18 | — | — | CN | disclosed |