Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.37 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28922132 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EKMT2AFNTAFNTB | |
| Alanine SCHEMBL29260750 | 0.87 | KDM4E (0.46) | SMN1; SMN2KDM4EKMT2AFNTAFNTB | |
| Glycine SCHEMBL28224417 | 0.84 | L3MBTL1 (0.43) | SMN1; SMN2KDM4EKMT2AFNTAFNTB | |
| SCHEMBL14737917 | 0.84 | — | — | |
| Glycine SCHEMBL28153830 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EKMT2AFNTAFNTB | |
| Hydrochloric Acid SCHEMBL26917217 | 0.82 | KDM4E (0.46) | SMN1; SMN2KDM4EKMT2ACYP2D6L3MBTL1 | |
| Hydrochloric Acid SCHEMBL14737787 | 0.82 | KDM4E (0.46) | SMN1; SMN2KDM4EKMT2ACYP2D6L3MBTL1 | |
| Bromide SCHEMBL28272602 | 0.82 | KDM4E (0.46) | SMN1; SMN2KDM4EKMT2ACYP2D6L3MBTL1 | |
| Iodide SCHEMBL30442896 | 0.82 | KDM4E (0.46) | SMN1; SMN2KDM4EKMT2ACYP2D6L3MBTL1 | |
| Glycine SCHEMBL31228162 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EKMT2AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118718762-A | Amino ion liquid grafted polyamide thin layer composite nanofiltration membrane and preparation method thereof | 杭州师范大学 | 2024-10-01 | — | — | CN | claimed |
| CN-118079649-A | Preparation method of nanofiltration membrane for regulating and controlling membrane surface charge | 江苏泷膜科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2025044226-A1 | PREPARATION METHOD FOR NANOFILTRATION MEMBRANE FOR REGULATING AND CONTROLLING MEMBRANE SURFACE CHARGES | 江苏泷膜科技有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-118079649-A | Preparation method of nanofiltration membrane for regulating and controlling membrane surface charge | 江苏泷膜科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115196663-B | Preparation method of controllable nano calcium carbonate | 邹平县晟昶钙业有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116078169-A | Polyamide composite nanofiltration membrane modified by multi-reactive group ionic liquid and preparation method and application thereof | 杭州师范大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-115678096-A | Acid-alkali-resistant hydrophilic polydopamine/ionic liquid coating and preparation method thereof | 杭州师范大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-115196663-A | Preparation method of controllable nano calcium carbonate | 中国科学院兰州化学物理研究所 | 2022-10-18 | — | — | CN | disclosed |