Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.34 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28224417 | 0.88 | L3MBTL1 (0.43) | SMN1; SMN2KDM4EL3MBTL1KMT2AFNTA | |
| Bromide SCHEMBL28540808 | 0.86 | L3MBTL1 (0.41) | SMN1; SMN2KDM4EL3MBTL1KMT2ACYP2D6 | |
| Glycine SCHEMBL28864321 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EL3MBTL1KMT2AFNTA | |
| Glycine SCHEMBL31228165 | 0.79 | KDM4E (0.45) | SMN1; SMN2KDM4EL3MBTL1KMT2AFNTA | |
| Glycine SCHEMBL31228168 | 0.79 | KDM4E (0.45) | SMN1; SMN2KDM4EL3MBTL1KMT2AFNTA | |
| Glycine SCHEMBL28922132 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EL3MBTL1KMT2AFNTA | |
| SCHEMBL28702194 | 0.79 | TLR8 (0.41) | KDM4EL3MBTL1KMT2ACYP2D6ARG1 | |
| SCHEMBL29137079 | 0.77 | TLR8 (0.44) | KDM4EL3MBTL1KMT2ACYP2D6MAPT | |
| Alanine SCHEMBL29639361 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2KDM4EL3MBTL1KMT2AFNTA | |
| Alanine SCHEMBL28224416 | 0.77 | L3MBTL1 (0.43) | SMN1; SMN2KDM4EL3MBTL1KMT2AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118718762-A | Amino ion liquid grafted polyamide thin layer composite nanofiltration membrane and preparation method thereof | 杭州师范大学 | 2024-10-01 | — | — | CN | claimed |
| CN-118718762-A | Amino ion liquid grafted polyamide thin layer composite nanofiltration membrane and preparation method thereof | 杭州师范大学 | 2024-10-01 | — | — | CN | disclosed |