Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864344 | 1.00 | RIPK1 (0.51) | RIPK1MAPTGABBR2GABBR1ALDH1A1 | |
| SCHEMBL13446248 | 0.81 | RIPK1 (0.49) | RIPK1GAALMNAHSD17B10MEN1 | |
| SCHEMBL23344877 | 0.79 | RIPK1 (0.53) | RIPK1MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL9736992 | 0.78 | GABBR2 (0.53) | MAPTGABBR2GABBR1ALDH1A1GAA | |
| SCHEMBL13594310 | 0.77 | RIPK1 (0.51) | RIPK1LMNAMEN1KMT2A | |
| Butane SCHEMBL10411229 | 0.77 | GABBR2 (0.48) | MAPTGABBR2GABBR1ALDH1A1GAA | |
| SCHEMBL13351981 | 0.76 | RIPK1 (0.50) | RIPK1MAPTLMNA | |
| SCHEMBL25512616 | 0.76 | RIPK1 (0.50) | RIPK1MAPTL3MBTL1LMNAPOLB | |
| SCHEMBL29028831 | 0.76 | GABBR2 (0.44) | MAPTGABBR2GABBR1ALDH1A1GAA | |
| SCHEMBL5918594 | 0.75 | GABBR2 (0.47) | MAPTGABBR2GABBR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197098-A | Cell necrosis inhibitor | 北京生命科学研究所 | 2022-10-18 | — | — | CN | disclosed |