Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 3/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | STIM1 | Q13586 | 4/20 | 0.52 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864465 | 0.91 | STIM1 (0.48) | OGTMKNK1MKNK2OPRD1P2RY14 | |
| SCHEMBL2488476 | 0.79 | MKNK1 (0.77) | MKNK1MKNK2 | |
| SCHEMBL26628304 | 0.79 | STIM1 (0.76) | OGTOPRD1P2RY14SIGMAR1STIM1 | |
| SCHEMBL29946192 | 0.79 | STIM1 (0.76) | OGTOPRD1P2RY14SIGMAR1STIM1 | |
| SCHEMBL26628312 | 0.78 | PTGS2 (0.67) | OGTPTGS2CA12CA2CA9 | |
| SCHEMBL30093108 | 0.76 | GABRA1 (0.50) | OGTP2RY14PTGS2CA12CA2 | |
| SCHEMBL29269323 | 0.76 | OGT (0.61) | OGTOPRD1P2RY14SIGMAR1STIM1 | |
| SCHEMBL30166588 | 0.75 | MAP4K4 (0.53) | MKNK1MKNK2 | |
| SCHEMBL20240506 | 0.75 | MAP4K4 (0.53) | MKNK1MKNK2 | |
| SCHEMBL21122080 | 0.73 | STIM1 (0.65) | OGTOPRD1P2RY14SIGMAR1STIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115243765-A | Biphenyl compounds as SOCE modulators, compositions and uses thereof | 皮埃蒙特阿米阿伏伽德罗东方大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115243765-A | Biphenyl compounds as SOCE modulators, compositions and uses thereof | 皮埃蒙特阿米阿伏伽德罗东方大学 | 2022-10-25 | — | — | CN | disclosed |