Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 5/20 | 0.65 |
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | CA5A | P35218 | 2/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | STIM1 | Q13586 | 3/20 | 0.57 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.57 |
| ▸ | OGT | O15294 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26628314 | 0.97 | PTGS2 (0.67) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL12420365 | 0.94 | PTGS2 (0.67) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL27903094 | 0.92 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL22833938 | 0.89 | CYP1B1 (0.63) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL28320917 | 0.86 | PTGS2 (0.69) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL28148254 | 0.86 | PTGS2 (0.69) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL16460181 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL18031105 | 0.85 | PTGS2 (0.67) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL26628312 | 0.83 | PTGS2 (0.67) | PTGS2PTGS1CA1CA2CA5A | |
| SCHEMBL182731 | 0.83 | STIM1 (0.66) | PTGS2PTGS1CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | claimed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-110563659-B | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-110563659-A | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2019-12-13 | — | — | CN | disclosed |
| CN-106588787-B | A kind of application of the triazole of 1,2,3- containing sweet-smelling formacyl ligand | 昆明理工大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-106588788-B | The method of one pot of two-step method synthesis 1,2,3- triazole compound | 河南师范大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-106588787-A | Arylformyl group-containing 1,2,3-triazole ligand, and preparation method and application thereof | 昆明理工大学 | 2017-04-26 | — | — | CN | disclosed |
| US-9375705-B2 | Heterogeneous copper nanocatalyst and manufacturing methods thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2016-06-28 | — | — | US | disclosed |
| US-8877676-B2 | Heterogeneous copper nanocatalyst and manufacturing methods thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2014-11-04 | — | — | US | disclosed |
| US-8877676-B2 | Heterogeneous copper nanocatalyst and manufacturing methods thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2014-11-04 | — | — | US | disclosed |
| US-8877676-B2 | Heterogeneous copper nanocatalyst and manufacturing methods thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2014-11-04 | — | — | US | disclosed |
| US-20140302984-A1 | HETEROGENEOUS COPPER NANOCATALYST AND MANUFACTURING METHODS THEREOF | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2014-10-09 | — | — | US | disclosed |
| US-20130096165-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2013-04-18 | — | — | US | disclosed |
| US-8362050-B2 | Compounds and methods for modulating G protein-coupled receptors | IRM LLC (BM) | 2013-01-29 | — | — | US | disclosed |
| US-20110172278-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2011-07-14 | — | — | US | disclosed |
| US-20110172417-A1 | Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2011-07-14 | — | — | US | disclosed |
| US-20110172417-A1 | Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2011-07-14 | — | — | US | disclosed |
| US-20110172417-A1 | Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172417-A1 | Heterogeneous Copper Nanocatalyst and Manufacturing Methods Thereof | AOC3, AOC2, USP13 | PTGS2 1329/4885PTGS1 1730/4885CA1 423/4885 |
| US-20130096165-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | GRK2, GRK3, GPR3 | PTGS2 481/4885PTGS1 440/4885CA1 4087/4885 |
| US-20110172278-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | GRK2, GRK3, GPR3 | PTGS2 481/4885PTGS1 440/4885CA1 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.