Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864611 | 1.00 | HSD17B10 (0.50) | HSD17B10PDK1KDM1AWNT1GSK3B | |
| SCHEMBL715037 | 1.00 | HSD17B10 (0.50) | HSD17B10PDK1KDM1AWNT1GSK3B | |
| Hydrochloric Acid SCHEMBL5092822 | 0.98 | HSD17B10 (0.48) | HSD17B10PDK1KDM1AWNT1GSK3B | |
| Trifluoroacetic Acid SCHEMBL28864626 | 0.91 | HSD17B10 (0.42) | HSD17B10PDK1KDM1AWNT1GSK3B | |
| Trifluoroacetic Acid SCHEMBL28864610 | 0.91 | HSD17B10 (0.42) | HSD17B10PDK1KDM1AWNT1GSK3B | |
| SCHEMBL8570719 | 0.85 | PDK1 (0.43) | HSD17B10PDK1KDM1AWNT1GSK3B | |
| SCHEMBL24576809 | 0.84 | KDM4E (0.53) | PDK1KDM1AWNT1GSK3BDYRK1A | |
| SCHEMBL12234170 | 0.84 | KDM4E (0.53) | PDK1KDM1AWNT1GSK3BDYRK1A | |
| SCHEMBL28966115 | 0.84 | PDK1 (0.42) | HSD17B10PDK1KDM1AWNT1GSK3B | |
| SCHEMBL500093 | 0.82 | GLA (0.53) | HSD17B10PDK1KDM1AWNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |