Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864556 | 1.00 | PLA2G10 (0.38) | PLA2G10PLA2G5PDK1USP2SMN1; SMN2 | |
| SCHEMBL28864624 | 1.00 | PLA2G10 (0.38) | PLA2G10PLA2G5PDK1USP2SMN1; SMN2 | |
| SCHEMBL12233169 | 0.83 | PDK1 (0.40) | PDK1SMN1; SMN2GLRA1WNT1GSK3B | |
| SCHEMBL28864640 | 0.82 | HRH3 (0.39) | PLA2G10PLA2G5PDK1USP2SMN1; SMN2 | |
| SCHEMBL28864621 | 0.82 | HRH3 (0.39) | PLA2G10PLA2G5PDK1USP2SMN1; SMN2 | |
| SCHEMBL28864578 | 0.81 | MEN1 (0.42) | PLA2G10PLA2G5SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28864553 | 0.81 | MEN1 (0.42) | PLA2G10PLA2G5SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28864583 | 0.80 | PLA2G10 (0.33) | PLA2G10PLA2G5USP2SMN1; SMN2WNT1 | |
| SCHEMBL715037 | 0.77 | HSD17B10 (0.50) | PDK1GLRA1WNT1GSK3BDYRK1A | |
| SCHEMBL8570719 | 0.77 | PDK1 (0.43) | PDK1GLRA1WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |