Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864621 | 1.00 | HRH3 (0.39) | HRH3PDK1NR1H2KDM4EALDH1A1 | |
| SCHEMBL28864556 | 0.82 | PLA2G10 (0.38) | PDK1NR1H2KDM4EALDH1A1HTR4 | |
| SCHEMBL28864624 | 0.82 | PLA2G10 (0.38) | PDK1NR1H2KDM4EALDH1A1HTR4 | |
| SCHEMBL28864628 | 0.82 | PLA2G10 (0.38) | PDK1NR1H2KDM4EALDH1A1HTR4 | |
| SCHEMBL12226471 | 0.79 | PDK1 (0.44) | HRH3PDK1 | |
| SCHEMBL12226474 | 0.79 | PDK1 (0.44) | HRH3PDK1 | |
| SCHEMBL12226473 | 0.79 | PDK1 (0.44) | HRH3PDK1 | |
| SCHEMBL28864583 | 0.78 | PLA2G10 (0.33) | ALDH1A1HTR4PLA2G10PLA2G5RECQL | |
| SCHEMBL28864592 | 0.77 | HSD17B10 (0.48) | HRH3PDK1KDM4E | |
| SCHEMBL169122 | 0.77 | HSD17B10 (0.48) | HRH3PDK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |