Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | MET | P08581 | 3/20 | 0.50 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870157 | 1.00 | PDGFRB (0.52) | PDGFRBPDGFRAMETTNIKPIK3CD | |
| SCHEMBL27988662 | 0.80 | PDGFRB (0.44) | PDGFRBPDGFRAMETTNIKPIK3CD | |
| SCHEMBL28687573 | 0.77 | MET (0.58) | MET | |
| SCHEMBL29870068 | 0.77 | MET (0.58) | MET | |
| SCHEMBL29870024 | 0.76 | EGFR (0.48) | PDGFRBPDGFRAMETTNIKPIK3CA | |
| SCHEMBL15686689 | 0.73 | PDGFRB (0.40) | PDGFRBPDGFRAMETTNIK | |
| SCHEMBL29377660 | 0.73 | PDGFRB (0.53) | PDGFRBPDGFRAMETPIK3CDPIK3CA | |
| SCHEMBL30998838 | 0.72 | CYP1A2 (0.46) | — | |
| Hydrochloric Acid SCHEMBL30939459 | 0.72 | ADRB2 (0.48) | EGFR | |
| Hydrochloric Acid SCHEMBL29227874 | 0.72 | ADRB2 (0.48) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |