SCHEMBL28864994

SCHEMBL28864994

CC(OC(C)c1ccccc1NCc1ccccc1)c1ccccc1NCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.49
KDM4E B2RXH2 3/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
POLB P06746 2/20 0.42
BACE1 P56817 1/20 0.42
HTT P42858 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
APAF1 O14727 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
IDO1 P14902 1/20 0.40
ADRA2C P18825 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12859084 0.84 HSD17B10 (0.53) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL10490374 0.81 HSD17B10 (0.50) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL28745521 0.77 KDM4E (0.54) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL30464743 0.74 HSD17B10 (0.71) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL4571036 0.74 HSD17B10 (0.71) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL14686239 0.74 HSD17B10 (0.50) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL17468739 0.72 HSD17B10 (0.49) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL6953610 0.72 HSD17B10 (0.49) HSD17B10KDM4EHPGDTSHRPOLB
SCHEMBL8935356 0.71 HSD17B10 (0.44) HSD17B10KDM4EHPGDPOLBBACE1
SCHEMBL7397108 0.70 POLB (0.48) HSD17B10KDM4EHPGDPOLBBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115068346-A Dental photocurable composition having excellent handling properties and storage stability 株式会社松风 2022-09-20 CN disclosed
CN-115068348-A Curable composition for dental use having excellent storage stability 株式会社松风 2022-09-20 CN disclosed